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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FIGN All Species: 10.3
Human Site: S416 Identified Species: 15.11
UniProt: Q5HY92 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5HY92 NP_060556.2 759 82146 S416 N S L G S R S S E S F G K Y T
Chimpanzee Pan troglodytes XP_001153855 674 74011 Q357 G E Q N G G M Q C K P Y G A G
Rhesus Macaque Macaca mulatta XP_001097992 759 82110 S416 N S L G S R S S E S F G K Y T
Dog Lupus familis XP_545496 695 74019 L378 R P L L P H G L Q G P A L R A
Cat Felis silvestris
Mouse Mus musculus Q9ERZ6 759 82080 S416 N S L G S R S S E S F G K Y T
Rat Rattus norvegicus Q6GX84 677 74178 K360 S E Q N G N V K P K S S R A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506217 731 78137 A413 G G V A N G G A R C G P R A A
Chicken Gallus gallus Q5ZK92 613 66247 N296 A P K N S R T N K P S T P T P
Frog Xenopus laevis Q6DDU8 655 72133 S337 R Q E D V E D S N R K V Y G Q
Zebra Danio Brachydanio rerio Q503S1 736 79183 D412 F G S P V M S D H G D D S R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQN8 523 58530 P206 V S S N F V S P V A Q N D N S
Honey Bee Apis mellifera XP_625184 585 66969 N268 K I Q E N M Y N N E I D T M E
Nematode Worm Caenorhab. elegans O16299 594 66169 G277 G M D T E G G G K D E K M S G
Sea Urchin Strong. purpuratus XP_783737 603 65189 S286 R N G S G G Q S G S M S N N N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SEX2 523 57218 D206 S M N G D A E D G K S K R G L
Baker's Yeast Sacchar. cerevisiae P39955 897 100313 A507 S K P Y S H G A S Q N K K P S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.6 99.4 72.9 N.A. 97.8 35.5 N.A. 31.6 24.8 35.7 71.2 N.A. 25.2 26.6 26.4 30.8
Protein Similarity: 100 54.9 99.4 79.1 N.A. 99.3 54.9 N.A. 47 42.2 53.4 83.7 N.A. 40.8 46.6 43.3 46.9
P-Site Identity: 100 0 100 6.6 N.A. 100 0 N.A. 0 13.3 6.6 6.6 N.A. 13.3 0 0 13.3
P-Site Similarity: 100 0 100 13.3 N.A. 100 13.3 N.A. 26.6 33.3 6.6 6.6 N.A. 26.6 13.3 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. 23.9 25 N.A.
Protein Similarity: N.A. N.A. N.A. 39.2 40.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 7 0 7 0 13 0 7 0 7 0 19 13 % A
% Cys: 0 0 0 0 0 0 0 0 7 7 0 0 0 0 0 % C
% Asp: 0 0 7 7 7 0 7 13 0 7 7 13 7 0 0 % D
% Glu: 0 13 7 7 7 7 7 0 19 7 7 0 0 0 7 % E
% Phe: 7 0 0 0 7 0 0 0 0 0 19 0 0 0 0 % F
% Gly: 19 13 7 25 19 25 25 7 13 13 7 19 7 13 19 % G
% His: 0 0 0 0 0 13 0 0 7 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 7 7 7 0 0 0 0 7 13 19 7 19 25 0 0 % K
% Leu: 0 0 25 7 0 0 0 7 0 0 0 0 7 0 7 % L
% Met: 0 13 0 0 0 13 7 0 0 0 7 0 7 7 0 % M
% Asn: 19 7 7 25 13 7 0 13 13 0 7 7 7 13 7 % N
% Pro: 0 13 7 7 7 0 0 7 7 7 13 7 7 7 7 % P
% Gln: 0 7 19 0 0 0 7 7 7 7 7 0 0 0 13 % Q
% Arg: 19 0 0 0 0 25 0 0 7 7 0 0 19 13 0 % R
% Ser: 19 25 13 7 32 0 32 32 7 25 19 13 7 7 13 % S
% Thr: 0 0 0 7 0 0 7 0 0 0 0 7 7 7 19 % T
% Val: 7 0 7 0 13 7 7 0 7 0 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 7 0 0 0 0 7 7 19 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _